Дихлормид

Description

Dichlormide is a “safety” antidote for herbicides, a substance from the dichloroacetamide group, used not as an independent pesticide, but as a protective additive to herbicide preparations. Activates metabolic pathways for the detoxification of foreign compounds in crop plants, reducing the phytotoxicity of the herbicide for the target crop without losing its effectiveness against weeds.

Basic Attributes

• CAS No: 37764-25-3 (also found as 11140-95-7)
• Chemical formula: C8H11Cl2NO
• Synonyms: N,N-Diallyl-2,2-dichloroacetamide, R 25788, N,N-Diallyldichloroacetamide, Stauffer R 25788
• Molecular weight: 208.09
• Exact weight: 208.09
• EU number: 253-658-8
• UNII: E901J4382O
• DSSTox ID: DTXSID4027997
• PSA specifications: 20.3
• XLogP3: 2.4

Physico-chemical characteristics

• Color/form: transparent viscous liquid
• Appearance: yellow transparent liquid

The density value is given in the source without a number (the line breaks at the word “Density:”), so it is not included in the passport - unreliable data is not substituted. Other constants (melting, boiling, flash points, refractive index) are also absent from the dump.

Scope of application

Dichloromide is a safener officially used (including approved by the U.S. Environmental Protection Agency) to protect corn, pastures, and corn stalks from damage from chloroacetanilide and thiocarbamate herbicides. Belongs to the class of dichloroacetamide safeners that provide protection to corn, wheat and rice from damage by herbicides butachlor, metolachlor and other chloroacetanilides and thiocarbamates when applied pre-emergence.

Mechanism of action

The main mechanism is the activation in the tissues of the cultivated plant of metabolic pathways for the detoxification of foreign compounds, primarily an increase in the activity of glutathione-S-transferase. This accelerates the conjugation of the herbicide with glutathione and its subsequent neutralization in the culture cells, while weeds, in which this mechanism is less pronounced, remain sensitive to the herbicide. This mode of action fundamentally distinguishes Seifner from a conventional pesticide: dichlormide itself does not kill weeds or protect against pests - it only selectively increases the resistance of the crop plant to the herbicide already used.

Security Properties

According to independent sources: acute oral toxicity LD50 in rats is about 2000 mg/kg, inhalation LC50 for 4 hours is about 11 mg/l; the substance does not irritate the skin and eyes. Easily soluble in water, highly volatile from aqueous solutions, and, as a rule, does not persist in soil, which reduces the risk of accumulation in the soil profile when regularly used as part of herbicide mixtures.

Storage and transportation conditions

Store in an airtight container in a cool, dry place, separate from food and feed. As a liquid agrochemical component, it requires standard handling precautions: gloves, eye protection, ventilated workplace. Commercial preparations of dichlormide are usually supplied in the form of ready-made mixtures with the target herbicide, therefore storage conditions in the warehouse are determined collectively by the safety data sheet of the finished formulation.