Пиперлотин С

Description

Piperlotin C is an amide alkaloid, (2E)-1-(1-pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one. Geometric isomer of piperlotine D with E configuration of the double bond. Isolated from pepper plants: described in the Piper nigrum herbs and in the Piper lolot amides. The structure combines three elements - a trimethoxy-substituted benzene ring, a conjugated double bond and an amide group closed in a pyrrolidine ring.

Basic Attributes

• CAS No: 886989-88-4
• Chemical formula: C16H21NO4
• Molecular Weight: 291.34224
• Exact weight: 291.147
• PSA Specifications: 48
• XLogP3: 2.2
• Synonyms: Piperlotine C, (2E)-1-(1-pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one

Activity studied

• pronounced suppression of platelet aggregation

The compound belongs to the series of piperlotins A–L, obtained by separating the methanolic extract of Piper lolot under the control of an anti-aggregation test. The original extract inhibited platelet aggregation caused by arachidonic acid and platelet activating factor.

Scope of application

• standard for chromatographic and mass spectrometric analysis of pepper raw materials
• sample comparison for the isolation and identification of natural amides
• test compound in platelet aggregation studies
• pair with the Z-isomer (piperlotin D) to study the role of double bond geometry

Storage and handling

Reagent for laboratory tasks. Store in a tightly closed container, away from light and moisture. Protective equipment: gloves, safety glasses, working with powder under traction. Values ​​for phase transition temperatures, solubility, toxicity indicators, GHS classification and transport codes are not included in the product card.