Меарнситрин

Description

Mearnsitrin is a flavonol glycoside, 3-O-α-L-rhamnopyranoside of mearnsitrin. In relation to myricitrin, this is its 4'-methyl ester, hence the synonym 4'-methylmyricitrin. The aglycone is mearnsetin, the sugar component is rhamnose, attached at the hydroxyl position 3. Isolated from the bark of Clausena excavata, leaves of Leea guineense and the aerial part of Goniothalamus thwaitesii; a related 7-O-methylmearnsitrin has been described from the leaves of Sageretia theezans with antioxidant effects. Like other flavonoids, it is used as a natural coloring agent.

Basic Attributes

• CAS No: 30484-88-9 (related registrations 11039-35-3, 28759-36-6, 230283-38-2)
• Gross formula: C22H22O12
• Molecular Weight: 478.40288
• Exact weight: 478.40
• PSA Specs: 196
• XLogP3: 0.8

Structure

• Systematic name: 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2-(3,5-dihydroxy-4-methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
• Class: O-glycosides flavonols
• Hydroxyls at positions 5 and 7 of ring A, two hydroxyls and a methoxy group on ring B, rhamnoside at C-3
• The large polar surface 196 and close to zero XLogP3 explain the solubility in aqueous-alcoholic media and poor retention on the reverse phase

Scope of application

• standard sample for the chromatographic determination of flavonol glycosides in plant materials, extracts and dietary supplements
• marker of authenticity of extracts from listed plant sources
• object of research on the antioxidant activity of flavonoids
• natural dye

Safety Information

• WGK Germany: 3

Storage and handling

Storage conditions: minus 20 °C. Keep the container tightly closed, protect from light and moisture - flavonol glycosides are sensitive to oxidation and hydrolysis. Hazard class for the aquatic environment WGK 3 excludes the discharge of solutions and washes into the sewer system. Selection of samples should be carried out with gloves, without dust.